Wuhan virus 2020 - Page 590

Rockstar · 10-05-21, 09:29 PM

Skybird · 10-05-21, 10:22 PM

Singapore, of 1512 hospitalized on Octobre 5th, only 34 are in ICU (~10% of their current ICU capacity of 300, which they say they can boost to 1000 if need would be).

Will you ever finally get it? The vaccine only lowers a bit the rate of infeciton. But the vaccine prevents (= dramatically reduces likelihood of) infections killing you.

A safety belt does not prevent accidents. It only prevents you from flying through the windshield and slitting your throat if you hit that tree ahead.

Skybird · 10-06-21, 01:30 AM

The Neue Zürcher Zeitung writes:

At the moment, a basic knowledge of the Greek alphabet is proving to be helpful: Since June, the questionable and observable variants of the Sars-CoV-2 coronavirus have been using Greek letters as "trivial names" in addition to their scientific names, and we are already at Lambda. The organization currently considers four variants to be questionable, “Variants of Concern”: Alpha, Beta, Gamma and Delta. Four more are “Variants of Interest”. Others turned out to be more harmless than feared and were declassified; They kept their names anyway, Epsilon for example. How many new letters will be added in the course of the year is unclear. At best, it would be surprising if the list of variants still ended with Lambda at the end of the year.

Fortunately, the vaccines currently available appear to be effective against either variant. However, that does not mean that we can rest on this success. Instead, we should start thinking about the future of vaccinations now and adapt them systematically to new variants: How should, for example, be determined when new vaccinations are needed and against which variants they should be directed? Research also needs to be pushed forward. Important data are still missing. And last but not least, it is important to actually use the existing vaccines to put as many obstacles in the way as possible for the spread of Sars-CoV-2.

Because the virus has only one goal: to spread as efficiently as possible. To do this, it has to adapt better and better to people. The genetic changes that allow it to do this, however, occur only randomly while the virus multiplies in infected cells. The most successful combination of such changes currently has the delta variant.

Your recipe for success is simple: Delta spreads faster from person to person than other Sars-CoV-2 variants and virtually snatches the hosts away from them. After infection, these are initially immune, the other variants lose out. But even if the virus has succeeded in another big hit with Delta - its path is actually a little bit rockier.

Because at the beginning of its triumphal march, the pathogen had around 8 billion potential hosts. He had never met their immune systems before and was accordingly unprepared. The virus was able to spread without resistance. That has changed in the meantime. To date, approximately 5.8 billion doses of vaccine have been administered worldwide, and nearly 43 percent of the world's population is fully vaccinated with two doses. They can all counter the virus with their immune protection.

This is a godsend. Because mutations can only arise if the pathogen multiplies. The higher the percentage of protected people, the less chance the virus has of changing. This in turn lowers the risk of developing variants that escape immune protection. But that also means that the proportion of people who have been vaccinated should be increased worldwide.

In some places this means attracting more people to vaccinations: creating incentives and explaining where the benefits for individuals and where the benefits for the common good lie. In many places, however, also to make vaccines accessible to enough people in the first place. If, for example, it is foreseeable in a country that vaccines cannot be inoculated quickly enough and threaten to expire, they should be distributed as efficiently as possible to those countries that need vaccines.

But the fact that efficient vaccines exist - even if their distribution is still faced with problems - does not mean that the research and development work is now done. It is still important to collect and evaluate data, such as antibody titers to be protected. Only on the basis of this information can immunologists and medical professionals decide when and for whom a third vaccine dose makes sense.

The work on the vaccines themselves remains just as important. Because the fact that we have effective vaccines does not mean that we no longer need others: For example, some researchers are working on so-called universal vaccines, which one day and possibly even different variants of Sars-CoV-2 protect other, related coronaviruses.

These vaccines would offer broad protection against many viruses of the same type. The fact that many of the "interesting" corona viruses are closely related gives rise to hope here. It would then be possible, for example, to use such universal vaccines as part of vaccines that are only directed against one virus variant, and thus perhaps to achieve a broader effect.

Nasal spray vaccinations against Covid-19 have also proven to be extremely efficient in initial studies on animals. They generate a good immune response on the mucous membranes - exactly where Sars-CoV-2 penetrates the body. Their development should also be followed up.

And last but not least, we should also think about the future of the vaccines that are already available: When, and ultimately from what loss of effectiveness of the vaccines, do we need adapted vaccines against certain variants? Which variants should these be directed against? And who determines it?

Dealing with the flu could serve as a model here: New variants of the various influenza viruses keep appearing, the spread and frequency of which are monitored using a special, worldwide reporting system. After evaluating these reports, a WHO expert group recommends twice a year - once for the southern and once for the northern hemisphere - which of these viruses the flu vaccines should target.

It remains to be seen whether the Sars-CoV-2 variants will ever develop that far apart, as well as whether different variants will one day dominate in different regions. With a coordinated collection and evaluation of data, one would be prepared for such possibilities.

Tracking influenza viruses is only part of the job, however. In addition, animal experiments and human sera are used to examine how well the vaccinations fight the viruses against which they are directed. A number of international laboratories are involved in this, some of which work within the framework of the Global Influenza Surveillance and Response System of the WHO, which are independent or associated with the Food and Agriculture Organization of the United Nations (FAO). If the effect observed in the laboratory falls to a certain extent, the vaccine virus is exchanged. Because flu viruses are constantly changing and after a few years manage to evade the immune system so much that new vaccine viruses are needed that contain the changes.

One could proceed in a similar way with Sars-CoV-2. To do this, however, it would first have to be very clear which antibody titers protect and up to which thresholds this protection is sufficient. This requires large-scale long-term studies in which the relevant data is collected and evaluated. In addition, coordinated monitoring of mutations is required in order to know exactly which variants are distributed where and how they develop genetically. There are also indications that some variants, as antigens, provide somewhat “broader” protection than others - if this is known exactly, they could be particularly suitable as models for vaccinations.

There is a lot to do and a lot to coordinate - across national borders. Now is the time to take this by hand. Sars-CoV-2 could one day become “more harmless” if the population is so immune to (multiple) infections and vaccinations that the disease progresses increasingly mildly. Until then, however, it means to confront the virus together.

Rockstar · 10-06-21, 06:42 AM

According to this fella “It makes no difference if you are vaccinated or not, statistically there is no difference.”

It’s also pretty obvious English is not his first language,

https://willemvincken.wordpress.com/...nces/#comments

And no, I am NOT “anti-vax”. Like everyone else here I got one. However I’m very much an anti-mandate kind of guy. According the article “it could have been worse had I not got vaccinated doesn’t seem to hold much water.”

Skybird · 10-06-21, 07:29 AM

How can lethality rates over a period of time have any meaning if they are not standardised in any way against the changes in treatment and prevention over that time period? And if growing effects from growing prevention rates do not get reflected?

Also ignored are the pporblems of Long Covid, and their eocniomic costs - which maybe ar ejigher than that of fatalities. Not to mention that surviving Coid but needing to be hospitalised can be an adventure lasting not weeks, but months.

Thats too shallow and one-dimensional for me what the man writes.

However I am, in Germany, in favour of slowly lifting the restriction regimes. There is strong empirical hint for letting it appear desirable to take the risk, how big or small it may be, of sitting out an ifneciton under the protective umbrella of being jabbed two times. That should tremendously reduce the risk of suffering a serious cause, while giving a severla factors as high immunity boost thna third booster jab does. That means, if their is a "right" time to get infected,m then it is in the 4-8 months after the second jab.

How it is once that time is over and immunity from vaccination has dropped even further, I cannot say. Obviously, like with most vaccinations, there is a critical treshhold level below which practic al immunity protection is no longer given (thats why many vaccinations should be repeated every lets say ten years or so: most vaccinations, though not all: a few work for all life).

AVGWarhawk · 10-06-21, 08:52 AM

Quote:

Originally Posted by Skybird

Singapore, of 1512 hospitalized on Octobre 5th, only 34 are in ICU (~10% of their current ICU capacity of 300, which they say they can boost to 1000 if need would be).

Will you ever finally get it? The vaccine only lowers a bit the rate of infeciton. But the vaccine prevents (= dramatically reduces likelihood of) infections killing you.

A safety belt does not prevent accidents. It only prevents you from flying through the windshield and slitting your throat if you hit that tree ahead.

Catfish · 10-06-21, 09:15 AM

Like Trump said, just the flu.

Arlo · 10-06-21, 09:16 AM

Quote:

Originally Posted by AVGWarhawk

(Amavingly 'brilliant' meme removed.)

The flu isn't Covid. Covid isn't the flu. Wait ... you know this, right?

AVGWarhawk · 10-06-21, 09:17 AM

Quote:

Originally Posted by Arlo

The flu isn't Covid. Covid isn't the flu. Wait ... you know this, right?

You a reading into this meme a bit to deeply. Just answer the question.

Arlo · 10-06-21, 09:19 AM

Quote:

Originally Posted by AVGWarhawk

You a reading into this meme a bit to deeply. Just answer the question.

If the question/meme is beside the point of the thread then what's the point?

AVGWarhawk · 10-06-21, 09:21 AM

Quote:

Originally Posted by Arlo

If the question/meme is beside the point of the thread then what's the point?

Do not answer a question with a question.

Arlo · 10-06-21, 09:23 AM

Quote:

Originally Posted by AVGWarhawk

Do not answer a question with a question.

Musta missed that forum rule.

Jimbuna · 10-06-21, 10:36 AM

Rockstar · 10-06-21, 10:38 AM

As of 1 Oct 21 202 deaths per day or 0.00006 percent of population and decreasing..

55.6 percent of population fully vaccinated

64.5 percent of population have received one dose

Moderna CEO five billion dollars richer. Loves long walk on the beach, the Covidian Cult, government and corporate mandates for vaccinations under Emergency Use Authorization. Weeeeeeeeeee

Jimbuna · 10-06-21, 10:39 AM

10-05-21, 09:29 PM	#8836
Rockstar Rear Admiral Join Date: Nov 2002 Location: Zendia Bar & Grill Posts: 11,876 Downloads: 10 Uploads: 0	__________________ Guardian of the honey and nuts Let's assume I'm right, it'll save time.

10-05-21, 10:22 PM	#8837
Skybird Soaring Join Date: Sep 2001 Location: the mental asylum named Germany Posts: 40,554 Downloads: 9 Uploads: 0	Singapore, of 1512 hospitalized on Octobre 5th, only 34 are in ICU (~10% of their current ICU capacity of 300, which they say they can boost to 1000 if need would be). Will you ever finally get it? The vaccine only lowers a bit the rate of infeciton. But the vaccine prevents (= dramatically reduces likelihood of) infections killing you. A safety belt does not prevent accidents. It only prevents you from flying through the windshield and slitting your throat if you hit that tree ahead. __________________ If you feel nuts, consult an expert.

10-06-21, 01:30 AM	#8838
Skybird Soaring Join Date: Sep 2001 Location: the mental asylum named Germany Posts: 40,554 Downloads: 9 Uploads: 0	The Neue Zürcher Zeitung writes: At the moment, a basic knowledge of the Greek alphabet is proving to be helpful: Since June, the questionable and observable variants of the Sars-CoV-2 coronavirus have been using Greek letters as "trivial names" in addition to their scientific names, and we are already at Lambda. The organization currently considers four variants to be questionable, “Variants of Concern”: Alpha, Beta, Gamma and Delta. Four more are “Variants of Interest”. Others turned out to be more harmless than feared and were declassified; They kept their names anyway, Epsilon for example. How many new letters will be added in the course of the year is unclear. At best, it would be surprising if the list of variants still ended with Lambda at the end of the year. Fortunately, the vaccines currently available appear to be effective against either variant. However, that does not mean that we can rest on this success. Instead, we should start thinking about the future of vaccinations now and adapt them systematically to new variants: How should, for example, be determined when new vaccinations are needed and against which variants they should be directed? Research also needs to be pushed forward. Important data are still missing. And last but not least, it is important to actually use the existing vaccines to put as many obstacles in the way as possible for the spread of Sars-CoV-2. Because the virus has only one goal: to spread as efficiently as possible. To do this, it has to adapt better and better to people. The genetic changes that allow it to do this, however, occur only randomly while the virus multiplies in infected cells. The most successful combination of such changes currently has the delta variant. Your recipe for success is simple: Delta spreads faster from person to person than other Sars-CoV-2 variants and virtually snatches the hosts away from them. After infection, these are initially immune, the other variants lose out. But even if the virus has succeeded in another big hit with Delta - its path is actually a little bit rockier. Because at the beginning of its triumphal march, the pathogen had around 8 billion potential hosts. He had never met their immune systems before and was accordingly unprepared. The virus was able to spread without resistance. That has changed in the meantime. To date, approximately 5.8 billion doses of vaccine have been administered worldwide, and nearly 43 percent of the world's population is fully vaccinated with two doses. They can all counter the virus with their immune protection. This is a godsend. Because mutations can only arise if the pathogen multiplies. The higher the percentage of protected people, the less chance the virus has of changing. This in turn lowers the risk of developing variants that escape immune protection. But that also means that the proportion of people who have been vaccinated should be increased worldwide. In some places this means attracting more people to vaccinations: creating incentives and explaining where the benefits for individuals and where the benefits for the common good lie. In many places, however, also to make vaccines accessible to enough people in the first place. If, for example, it is foreseeable in a country that vaccines cannot be inoculated quickly enough and threaten to expire, they should be distributed as efficiently as possible to those countries that need vaccines. But the fact that efficient vaccines exist - even if their distribution is still faced with problems - does not mean that the research and development work is now done. It is still important to collect and evaluate data, such as antibody titers to be protected. Only on the basis of this information can immunologists and medical professionals decide when and for whom a third vaccine dose makes sense. The work on the vaccines themselves remains just as important. Because the fact that we have effective vaccines does not mean that we no longer need others: For example, some researchers are working on so-called universal vaccines, which one day and possibly even different variants of Sars-CoV-2 protect other, related coronaviruses. These vaccines would offer broad protection against many viruses of the same type. The fact that many of the "interesting" corona viruses are closely related gives rise to hope here. It would then be possible, for example, to use such universal vaccines as part of vaccines that are only directed against one virus variant, and thus perhaps to achieve a broader effect. Nasal spray vaccinations against Covid-19 have also proven to be extremely efficient in initial studies on animals. They generate a good immune response on the mucous membranes - exactly where Sars-CoV-2 penetrates the body. Their development should also be followed up. And last but not least, we should also think about the future of the vaccines that are already available: When, and ultimately from what loss of effectiveness of the vaccines, do we need adapted vaccines against certain variants? Which variants should these be directed against? And who determines it? Dealing with the flu could serve as a model here: New variants of the various influenza viruses keep appearing, the spread and frequency of which are monitored using a special, worldwide reporting system. After evaluating these reports, a WHO expert group recommends twice a year - once for the southern and once for the northern hemisphere - which of these viruses the flu vaccines should target. It remains to be seen whether the Sars-CoV-2 variants will ever develop that far apart, as well as whether different variants will one day dominate in different regions. With a coordinated collection and evaluation of data, one would be prepared for such possibilities. Tracking influenza viruses is only part of the job, however. In addition, animal experiments and human sera are used to examine how well the vaccinations fight the viruses against which they are directed. A number of international laboratories are involved in this, some of which work within the framework of the Global Influenza Surveillance and Response System of the WHO, which are independent or associated with the Food and Agriculture Organization of the United Nations (FAO). If the effect observed in the laboratory falls to a certain extent, the vaccine virus is exchanged. Because flu viruses are constantly changing and after a few years manage to evade the immune system so much that new vaccine viruses are needed that contain the changes. One could proceed in a similar way with Sars-CoV-2. To do this, however, it would first have to be very clear which antibody titers protect and up to which thresholds this protection is sufficient. This requires large-scale long-term studies in which the relevant data is collected and evaluated. In addition, coordinated monitoring of mutations is required in order to know exactly which variants are distributed where and how they develop genetically. There are also indications that some variants, as antigens, provide somewhat “broader” protection than others - if this is known exactly, they could be particularly suitable as models for vaccinations. There is a lot to do and a lot to coordinate - across national borders. Now is the time to take this by hand. Sars-CoV-2 could one day become “more harmless” if the population is so immune to (multiple) infections and vaccinations that the disease progresses increasingly mildly. Until then, however, it means to confront the virus together. __________________ If you feel nuts, consult an expert.

10-06-21, 06:42 AM	#8839
Rockstar Rear Admiral Join Date: Nov 2002 Location: Zendia Bar & Grill Posts: 11,876 Downloads: 10 Uploads: 0	According to this fella “It makes no difference if you are vaccinated or not, statistically there is no difference.” It’s also pretty obvious English is not his first language, https://willemvincken.wordpress.com/...nces/#comments And no, I am NOT “anti-vax”. Like everyone else here I got one. However I’m very much an anti-mandate kind of guy. According the article “it could have been worse had I not got vaccinated doesn’t seem to hold much water.” __________________ Guardian of the honey and nuts Let's assume I'm right, it'll save time. Last edited by Rockstar; 10-06-21 at 06:57 AM.

10-06-21, 07:29 AM	#8840
Skybird Soaring Join Date: Sep 2001 Location: the mental asylum named Germany Posts: 40,554 Downloads: 9 Uploads: 0	How can lethality rates over a period of time have any meaning if they are not standardised in any way against the changes in treatment and prevention over that time period? And if growing effects from growing prevention rates do not get reflected? Also ignored are the pporblems of Long Covid, and their eocniomic costs - which maybe ar ejigher than that of fatalities. Not to mention that surviving Coid but needing to be hospitalised can be an adventure lasting not weeks, but months. Thats too shallow and one-dimensional for me what the man writes. However I am, in Germany, in favour of slowly lifting the restriction regimes. There is strong empirical hint for letting it appear desirable to take the risk, how big or small it may be, of sitting out an ifneciton under the protective umbrella of being jabbed two times. That should tremendously reduce the risk of suffering a serious cause, while giving a severla factors as high immunity boost thna third booster jab does. That means, if their is a "right" time to get infected,m then it is in the 4-8 months after the second jab. How it is once that time is over and immunity from vaccination has dropped even further, I cannot say. Obviously, like with most vaccinations, there is a critical treshhold level below which practic al immunity protection is no longer given (thats why many vaccinations should be repeated every lets say ten years or so: most vaccinations, though not all: a few work for all life). __________________ If you feel nuts, consult an expert.

10-06-21, 09:15 AM	#8842
Catfish Dipped Squirrel Operative Join Date: Sep 2001 Location: ..where the ocean meets the sky Posts: 16,897 Downloads: 38 Uploads: 0	Like Trump said, just the flu. __________________ >^..^<*)))>{ All generalizations are wrong.

10-06-21, 10:36 AM	#8848
Jimbuna Chief of the Boat Join Date: Feb 2006 Location: 250 metres below the surface Posts: 181,344 Downloads: 63 Uploads: 13	__________________ Wise men speak because they have something to say; Fools because they have to say something. Oh my God, not again!! GWX3.0 Download Page - Donation/instant access to GWX (Help SubSim)

10-06-21, 10:38 AM	#8849
Rockstar Rear Admiral Join Date: Nov 2002 Location: Zendia Bar & Grill Posts: 11,876 Downloads: 10 Uploads: 0	As of 1 Oct 21 202 deaths per day or 0.00006 percent of population and decreasing.. 55.6 percent of population fully vaccinated 64.5 percent of population have received one dose Moderna CEO five billion dollars richer. Loves long walk on the beach, the Covidian Cult, government and corporate mandates for vaccinations under Emergency Use Authorization. Weeeeeeeeeee __________________ Guardian of the honey and nuts Let's assume I'm right, it'll save time.

10-06-21, 10:39 AM	#8850
Jimbuna Chief of the Boat Join Date: Feb 2006 Location: 250 metres below the surface Posts: 181,344 Downloads: 63 Uploads: 13	__________________ Wise men speak because they have something to say; Fools because they have to say something. Oh my God, not again!! GWX3.0 Download Page - Donation/instant access to GWX (Help SubSim)