Iv'e been gone for a few days, pesky job and real life
After days of frustration I finally have a working SH5. Many thanks to all of you for your suggestions. I unloaded all the mods as suggested by Targor, changed my config file and saved properly as suggested by Silent Steel, and still no progress, game starts to load and then dumps me back to uplay. But then I disable TDW Ship Inertia as suggested by volodya61 and it works! So thanks again for all the help, now off to the west coast of Britain!