GWX was specifically designed not to be overly demanding on systems that already met the recommended specs for stock SH3. So chances are good that you will not see too much drop-off in performance (if any). You will probably see increased loading times, but most people that could run stock okay don't seem to have any problems running GWX once it loads.
Every system is different though, so let us know if you run into any snags. You could also post your specs and see if anything jumps out at the resident gurus as potentially problematic.
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