That's the main problem with any of the practical solutions and alternatives. There is always the possibility of a change to a situation between the time a trigger is pulled and when the munition reaches the location of its intended target...
As far as popping the bad guys when they come up for air, the really bad guys are smart enough to fly low and avoid the radar while engineering the activities of their lesser brethren. Remember, Bin Laden stayed indoors out of sight for several years, making it unlikely if not impossible to take an airborne "sniper shot". The same holds true for all the other senior leaders and planners in the Jihad; they stay well out of sight; sometimes the next time they are seen is the only chance you may have to eliminate them...
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