[propbeanie]

The wonderful world of Windows has changed a bit since you last played probably. Windows XP was the last "polite" version of Windows. Since then, Microsoft has introduced us to User Access Control (UAC) and other "goodies" that are ostensibly designed to protect us from ourselves. What this entails is a protection scheme on Microsoft's part that does not allow changes to the Program Files (x86) folder structure, especially anything with an exe, dll or cfg extension. Mods are rife with cfg files, so when you start the game up, Windows "sees" that someone has been naughty and changed the files in your game folder without Windows' authorization, so being the helpful curmudgeon that Windows is, it puts the original files back. So it ~looks~ like your mod activated fine, but in reality, it did not.

De-activate all the mods in the game and then un-install the game once again. You really shouldn't need to use a registry cleaner, unless you still have trouble after this, but just try to re-install the game. When it comes up with the screen with the install path, you want to change that from "C:\ Program Files (x86) \ Ubisoft \ Silent Hunter..." to something else. About the easiest thing to do is to just delete the "\ Program Files (x86)" part of the install path, and just use "C:\ Ubisoft \ Silent Hunter..." as the install folder. But use whatever you want to. Just do NOT install into the "root" C:\ drive, else you'll have similar issues. Once you are re-installed, try the mods again and see how you get along. If you've already done this, "oops" says I... we'll try something else.