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Old 12-08-21, 07:39 AM   #9433
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FOCUS writes:


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The Frankfurt virologist Sandra Ciesek has now announced the first results of laboratory tests. They confirm the fears regarding vaccination. Ciesek reported via Twitter on Wednesday that, according to their investigation, Omikron canceled the effect of the antibodies provoked by the vaccines compared to the Delta variant, which is currently dominant in Germany. Anyone who has been cross-vaccinated twice with Biontech, twice with Moderna or with Astrazeneca and Biontech will therefore no longer have any immune protection from the antibodies against the new variant after six months. “O percent neutralization” is the sobering result from Ciesek. There is then no longer any protection against infection with Corona. The data from Ciesek have not yet been reviewed by specialist colleagues and have not been published in a specialist magazine. Anyone who has been vaccinated twice with Biontech and has also received a booster vaccination is better protected against the new variant. According to Ciesek, the booster neutralizes at least 25 percent of Omikron three months after the vaccination. At Delta, on the other hand, the booster neutralizes the coronavirus by 95 percent.

According to Ciesek, this means: The protection provided by the booster against Omikron decreases by a factor of 37 compared to Delta. It is unclear how well the vaccination protects against severe Omicron courses "The data confirm that the development of a vaccine adapted to Omicron makes sense," continues Ciesek. However, the data she has now published could not say anything about whether the vaccination continues to protect against a severe course. The reason: It is not only the antibodies examined that are relevant, but also other parts of the immune system such as the so-called T cells. In addition, the results that have now been published are based on so-called neutralization tests. It looks at how many antibodies a vaccinated person has in the blood that can reach the virus variant and thus switch it off. The actual protection of vaccinated persons cannot be determined in this way. This requires clinical studies with thousands of test subjects or evaluations of the ongoing infection process.



Drosten: "Doesn't look good for people who have been vaccinated twice" Nevertheless, Christian Drosten also expressed concern about the new data via Twitter. "Now we have three groups with approximately 40-fold loss of serum neutralization activity in fully immunized individuals," he wrote. "Doesn't look good for a double vaccine," he concluded. A third dose is necessary. In a second tweet, Drosten made it clear again that a neutralization activity does not mean that the vaccination is 40 times less protective. "The real loss of immunity is much lower," explains Drosten. At the moment, therefore, triple vaccination is the best protection. Hence his urgent recommendation: "Don't wait, but boost."
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