Hey friend don't give up here! Do you perhaps have TheDarkWraith's new UI mod? Silent Hunter 5 is a big fat buggy mess and you should not just give up here. Now I think the only choice is to end the patrol in your naval base (Kiel, Bremen etc.) but that does not mean end the mission.
Ending a patrol is just basically getting a full repair done and upgrades and such which could be useful for you. Here is a tip for you when you are about to get depth charged. When you hear the destroyer or cruiser or whatever go over you go ahead flank and and do a hard to port or starboard which can really help in a situation like that as you take less damage to parts and such. Also make sure you are not on Silent running because that makes no repairs possible or reloading possible. If you have already been detected than don't worry about staying silent. Just avoid the depth charge and you won't get stuck.
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"Run Silent and Run Deep"
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