It has in the past for me using GWX 3.0.
Sometimes, for unknown reasons, SH 3 will just mess up a savegame. It has not happened to me in a while now since I have a computer with 8GB of ram, and use the 4GB patch. (Just watch now that I said that it will happen.) I do make alot of saves in game and, when it did happen, I could usually find one that would load. I think the farthest back I ever had to go was 3 saves to find one that would load.
